Investigation pathogenesis and genetic background of systemic autoimmune diseases.

Examination the clinical efficacy of diseases associated with systemic autoimmune diseases and the therapeutic methods used.

Investigating the pathogenesis of primary Sjögren's syndrome and IgG4-associated diseases.

Research of subgroups of systemic lupus erythematosus.

Study of clinical characteristics and pathogenesis of inflammatory myopathies.

Research on mixed connective tissue disease (MCTD).

Clinical and immunological effects of Extracorporal fotoferezis treatments in systemic sclerosis.

Interaction between Follikularis T-helper cells and B-cells and the role of regulatory T cells in autoimmune disorders.

Investigation of microRNAs involved in the differentiation and activation of T-helper and B cells.

Study of MicroRNA polymorphisms and expression patterns in Sjögren syndrome and systemic lupus erythematosus.

Pregnancy immunological studies.